Bioinformatics is the application of statistics and computer science to the field of molecular biology. The term Bioinformatics was coined by Paulicn Hogeweg in 1979 for the study of informalic processes in biotic systems. Its primary use, since at least the late 1980s, has been in genomics and genetics, particularly in those areas of genomics, involving large-scale DNA sequencing. Bioinformatics now entails the creation and advancement of databases, algorithms, computational and statistical techniques and theory to solve formal and practical problems, arising from the management and analysis of biological data.